Organismic: What is Too Much or Too Little?

Part of what an organismic system is constantly doing is figuring out 'what is too much?' A little 'hot' is ok, but when do you take off your coat, or when do you start to sweat, so you can cool yourself down? A little pain is ok, but—how much? What is your pain threshold and how does it change? How do you respond if you think you have hit that threshold? A successful organismic system needs good data, good reconciliation of that data, and a sensible idea of what is too much or too little.